A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking.
Walter NG, Chan PA, Hampel KJ, Millar DP, Burke JM, Biochemistry, 2001 Feb 27 - link

A conformational change in the "loop E-like" motif of the hairpin ribozyme is coincidental with domain docking and is essential for catalysis.
Hampel KJ, Burke JM, Biochemistry, 2001 Mar 27 - link