The CHMP4b- and Src-docking sites in the Bro1 domain are autoinhibited in the native state of Alix.
Zhou X, Pan S, Sun L, Corvera J, Lee YC, Lin SH, Kuang J, Biochem J, 2009 Mar 1 - link

The HIV-1 p6/EIAV p9 docking site in Alix is autoinhibited as revealed by a conformation-sensitive anti-Alix monoclonal antibody.
Zhou X, Pan S, Sun L, Corvera J, Lin SH, Kuang J, Biochem J, 2008 Sep 1 - link